Lateral pharyngoplasty versus uvulopalatopharyngoplasty: a clinical, polysomnographic and computed tomography measurement comparison

• Published in: Sleep (New York, N.Y.) Vol. 27; no. 5; pp. 942 - 950
• Main Authors: CAHALI, Michel B, FORMIGONI, Gilberto G. S, GEBRIM, Eloisa M. M. S, MIZIARA, Ivan D
• Format: Journal Article
• Language: English
• Published: Rochester, MN American Academy of Sleep Medicine 01.08.2004
• Subjects: Biological and medical sciences; Body Mass Index; Follow-Up Studies; Humans; Medical sciences; Non tumoral diseases; Oral Surgical Procedures; Otorhinolaryngologic Surgical Procedures; Otorhinolaryngology. Stomatology; Palate, Soft - surgery; Pharynx - surgery; Polysomnography - instrumentation; Postoperative Care; Preoperative Care; Prospective Studies; Sleep Apnea, Obstructive - diagnosis; Sleep Apnea, Obstructive - surgery; Sleep Stages - physiology; Tomography, X-Ray Computed; Treatment Outcome; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology; Uvula - surgery; Human; Electrodiagnosis; Sleep apnea syndrome; Uvulopalatoplasty; Upper respiratory tract; Surgery; Tomography; ENT disease; Polysomnography; Obstruction; Pharynx
• ISSN: 0161-8105; 1550-9109
• DOI: 10.1093/sleep/27.5.942

To compare the lateral pharyngoplasty procedure with uvulopalatopharyngoplasty (UPPP) in the treatment of obstructive sleep apnea hypopnea syndrome (OSAHS). Prospective randomized study. Academic tertiary center. Twenty-seven adults with OSAHS originally selected for treatment with UPPP. Patients were randomly assigned to 2 groups: in one group, we performed the lateral pharyngoplasty (15 cases), and in the other, we did the UPPP (12 cases). We compared treatment outcomes through the evaluation of OSAHS-related symptoms and the analysis of polysomnographic tests and computed tomography measurements of pharyngeal airway. The lateral pharyngoplasty group achieved a statistically greater reduction in body weight, excessive daytime sleepiness, and apnea-hypopnea index. In addition, only in this group did we observe a statistically significant increase in the amount of deep sleep stages and improvement in morning headaches. Patients from the UPPP group did not present significant changes in the polysomnographic parameters. Pharyngeal airway measurement outcomes were similar in both groups and did not reflect the clinical and polysomnographic differences we observed. Lateral pharyngoplasty produces better clinical and polysomnographic outcomes in the treatment of OSAHS than does UPPP, without resultant differences in the cross-sectional measurements of the pharyngeal airway between these treatments.