The facile synthesis of 5-formylporphyrin

A facile synthetic route of 5-formylporphyrin（2） has been developed.Using pyrrole and pivaldehyde as the starting materials,2 was obtained through several facile reactions.The synthetic route is easy to perform and can be scaled up,which gives the compound a better application perspective.

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Bibliographic Details
Published inChinese chemical letters Vol. 23; no. 5; pp. 505 - 508
Main Authors Liu, Peng Peng, Feng, Ya Qing, Gu, Cheng Zhi, Meng, Shu Xian, Zhang, Bao
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.05.2012
School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
Subjects
5-Formylporphyrin
Demetalation
Unsubstituted porphine
Vilsmeier reaction
原料使用
反应
合成路线
Unsubstituted porphine
Vilsmeier reaction
5-Formylporphyrin
Demetalation
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Summary:A facile synthetic route of 5-formylporphyrin（2） has been developed.Using pyrrole and pivaldehyde as the starting materials,2 was obtained through several facile reactions.The synthetic route is easy to perform and can be scaled up,which gives the compound a better application perspective.
Bibliography:5-Formylporphyrin; Unsubstituted porphine; Vilsmeier reaction; Demetalation
Peng Peng Liu,Ya Qing Feng~＊,Cheng Zhi Gu,Shu Xian Meng,Bao Zhang School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China
11-2710/O6
A facile synthetic route of 5-formylporphyrin（2） has been developed.Using pyrrole and pivaldehyde as the starting materials,2 was obtained through several facile reactions.The synthetic route is easy to perform and can be scaled up,which gives the compound a better application perspective.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2012.03.010