Multiple-detector responses or multiple-retention times: what is more informative for gas chromatography peak identification?

• Published in: Journal of Chromatography A Vol. 1047; no. 2; pp. 263 - 269
• Main Authors: Stoev, G., Mihailova, A.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier B.V 27.08.2004; Elsevier
• Subjects: Analytical chemistry; Chemistry; Chromatographic methods and physical methods associated with chromatography; Chromatography, Gas - methods; Detection, GC; Efficiency; Exact sciences and technology; Gas chromatographic methods; Reproducibility of Results; Retention times; Selectivity; Sensitivity; Sensitivity and Specificity; Sensitivity; Selectivity; Efficiency; Detection, GC; Retention times; Gas chromatography; Chemical analysis; Chromatographic retention; Qualitative analysis; Detection; Retention time; GC; Retention times; Efficiency; Selectivity; Sensitivity
• ISSN: 0021-9673
• DOI: 10.1016/j.chroma.2004.06.069

Multiple-separation and -detection are two approaches applied at the identification of analytes in chromatography. Using them depends on the physico-chemical properties and elemental content of the analytes. When physico-chemical properties are similar multiple-separation gives better opportunities for the identification. In this case, the efficiency of the columns is very important. When analytes contain some characteristic groups as NO 2, halogen, or nitrogen atoms then multiple-detection will be more useful. The sensitivity and/or selectivity of the detectors increase reliability of identification significantly.