Normal Retinal Vasculature Despite Familial Protein C Deficiency
It is unclear whether protein C deficiency is associated with retinal venous occlusive disease. We performed a cross-sectional study. Members of a protein C-deficient family, either deficient or nondeficient, with a history of nonocular venous thrombosis were included. All participants completed que...
Saved in:
Published in | American journal of ophthalmology Vol. 139; no. 5; pp. 944 - 945 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
New York, NY
Elsevier Inc
01.05.2005
Elsevier Elsevier Limited |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | It is unclear whether protein C deficiency is associated with retinal venous occlusive disease.
We performed a cross-sectional study.
Members of a protein C-deficient family, either deficient or nondeficient, with a history of nonocular venous thrombosis were included. All participants completed questionnaires regarding their medical and ophthalmic histories. Each subject underwent dilated direct ophthalmoscopic and binocular indirect ophthalmoscopic examinations by a single vitreoretinal specialist.
None of the 18 family members with a known history of nonocular thrombosis—12 with and 6 without protein C deficiency— manifested stigmas of recent or chronic retinal vascular occlusive disease.
This study showed no evidence of involvement of the retinal vascular bed in a family with an increased risk of nonocular venous thrombosis attributable to the deficiency of protein C. |
---|---|
Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0002-9394 1879-1891 |
DOI: | 10.1016/j.ajo.2004.11.036 |