Oral Microbiota and Pediatric Asthma Phenotype: A New Window for Biomarkers?

Ghedin and Huang discuss the study by Abdel-Aziz et al analyzing the microbiota of oropharyngeal swabs collected from 241 children recruited with mild, moderate, or severe school-age asthma or preschool wheezing as part of a multicenter European observational cohort study (U-BIOPRED [Unbiased Biomar...

Full description

Saved in:
Bibliographic Details
Published inAmerican journal of respiratory and critical care medicine Vol. 208; no. 2; pp. 119 - 121
Main Authors Ghedin, Elodie, Huang, Yvonne J.
Format Journal Article
LanguageEnglish
Published United States American Thoracic Society 15.07.2023
Subjects
Asthma
Asthma - diagnosis
Asthma - immunology
Biomarkers
Children & youth
Genotype & phenotype
Humans
Hypersensitivity
Microbiota
Microbiota - immunology
Pediatrics
Phenotype
Transcriptome
Online AccessGet full text

Cover

More Information
Summary:Ghedin and Huang discuss the study by Abdel-Aziz et al analyzing the microbiota of oropharyngeal swabs collected from 241 children recruited with mild, moderate, or severe school-age asthma or preschool wheezing as part of a multicenter European observational cohort study (U-BIOPRED [Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes]). The authors hypothesized that although no differences in microbial diversity were previously found to be associated with disease severity in this dataset, there could be compositional differences that correlate with clinically relevant phenotypes.
Bibliography:SourceType-Scholarly Journals-1
content type line 14
ObjectType-Editorial-2
ObjectType-Commentary-1
content type line 23
ObjectType-Article-3
ISSN:1073-449X
1535-4970
1535-4970
DOI:10.1164/rccm.202305-0856ED