Allele frequencies of six non-CODIS miniSTR loci (D1S1627, D3S4529, D5S2500, D6S1017, D8S1115 and D9S2157) in three South African populations

Abstract The allele frequency of six non-CODIS miniSTR loci: D1S1627, D3S4529, D5S2500, D6S1017, D8S1115 and D9S2157 were investigated in three South African populations (Afrikaner, Asian Indian and Mixed Ancestry). Deviation from Hardy–Weinberg equilibrium was observed in the Mixed Ancestry populat...

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Published inForensic science international : genetics Vol. 5; no. 4; pp. 354 - 355
Main Authors Abrahams, Zainonesa, D’Amato, Maria Eugenia, Davison, Sean, Benjeddou, Mongi
Format Journal Article
LanguageEnglish
Published Netherlands 01.08.2011
Subjects
DNA Fingerprinting
Ethnic Groups - genetics
Gene Frequency
Genetics, Population
Humans
Male
Microsatellite Repeats
Pathology
Polymerase Chain Reaction
South Africa
South Africa
MiniSTR
South Africa
Allele frequencies
Population data
DNA typing
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Summary:Abstract The allele frequency of six non-CODIS miniSTR loci: D1S1627, D3S4529, D5S2500, D6S1017, D8S1115 and D9S2157 were investigated in three South African populations (Afrikaner, Asian Indian and Mixed Ancestry). Deviation from Hardy–Weinberg equilibrium was observed in the Mixed Ancestry population for the locus D9S2157. All loci showed a moderate degree of polymorphism with heterozygosity values >0.6 for all populations. The combined power of discrimination was: 0.999997723, 0.999997163 and 0.99999961 for Afrikaner, Asian Indian and Mixed Ancestry populations, respectively. The respective values for the combined power of exclusion in these populations were: 0.99, 0.99 and 0.98.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ISSN:1872-4973
1878-0326
DOI:10.1016/j.fsigen.2010.01.019