The persistence in the human circulation of horse and human tetanus antitoxins

Human subjects were passively immunized with either horse-globulin tetanus antitoxin or human gamma globulin tetanus antitoxin. The homologous antitoxin persisted at higher levels and for a much longer period of time than the heterologous. The horseglobulin antitoxin decreased very sharply after the...

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Bibliographic Details
Published inThe Journal of pediatrics Vol. 59; no. 6; pp. 899 - 902
Main Authors Smolens, Joseph, Vogt, Agnes B., Crawford, Mary N., Stokes, Joseph
Format Journal Article
LanguageEnglish
Published United States Mosby, Inc 01.12.1961
Subjects
Animals
Antitoxins
Horses
Old Medline
Tetanus - immunology
Tetanus Antitoxin
Toxins, Biological
TETANUS/immunology
TOXINS AND ANTITOXINS
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Summary:Human subjects were passively immunized with either horse-globulin tetanus antitoxin or human gamma globulin tetanus antitoxin. The homologous antitoxin persisted at higher levels and for a much longer period of time than the heterologous. The horseglobulin antitoxin decreased very sharply after the first week, and, thereafter, followed a straight-line curve to its preimmunization level.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(61)80320-X