Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques

Fischer glycosylation is typically the chemical reaction of a monosaccharide and an alcohol in presence of an acidic catalyst to afford glycosides in pyranosidic and furanosidic forms. This reaction is still applied today for the synthesis of specialized glycosides, and optimization and modification...

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Published inTopics in current chemistry (2016) Vol. 380; no. 4; p. 26
Main Authors Haese, Matteo, Winterhalter, Kai, Jung, Jessica, Schmidt, Magnus S.
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.07.2022
Subjects
Catalysis
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Friends
Glycosides
Glycosylation
Humans
Life Sciences
Materials Science
Molecular Medicine
Physics
Review
Glycosides
Microwave
Flow reactor
Microreactor
Fischer glycosylation
Ultrasonic
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Summary:Fischer glycosylation is typically the chemical reaction of a monosaccharide and an alcohol in presence of an acidic catalyst to afford glycosides in pyranosidic and furanosidic forms. This reaction is still applied today for the synthesis of specialized glycosides, and optimization and modification of the method have continued since its discovery by Emil Fischer in the 1890s. This review presents advancements in Fischer glycosylation described in literature of the past 15 years and its implementation in modern chemical methods.
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ISSN:2365-0869
2364-8961
DOI:10.1007/s41061-022-00383-9