Radiation-induced spindle cell sarcoma: A rare case report

Ionizing radiation has been known to induce malignant transformation in human beings. Radiation-induced sarcomas are a late sequel of radiation therapy. Most sarcomas have been reported to occur after exposure to a radiation dose of 55 Gray (Gy) and above, with a dose ranging from 16 to 112 Gys. Spi...

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Bibliographic Details
Published inIndian journal of dental research Vol. 20; no. 3; pp. 380 - 384
Main Authors Khan, Mubeen, Chandramala, Rupa, Sharma, Ridhima, Vijayalakshmi, KR
Format Journal Article
LanguageEnglish
Published Mangalore Medknow Publications and Media Pvt. Ltd 01.07.2009
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Subjects
Care and treatment
Case studies
Complications and side effects
Diagnosis
Family medical history
Head and neck cancer
Histology
Ionizing radiations
Mutation
Radiation therapy
Radiotherapy
retinoblastoma
Risk factors
Sarcoma
Sinuses
spindle cell sarcomas
India
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Summary:Ionizing radiation has been known to induce malignant transformation in human beings. Radiation-induced sarcomas are a late sequel of radiation therapy. Most sarcomas have been reported to occur after exposure to a radiation dose of 55 Gray (Gy) and above, with a dose ranging from 16 to 112 Gys. Spindle cell sarcomas, arising after radiotherapy given to treat the carcinoma of head and neck region is a very uncommon sequel. This is a rare case report of spindle cell sarcoma of left maxilla, in a 24-year-old male, occurring as a late complication of radiotherapy with Cobalt-60 given for the treatment of retinoblastoma of the left eye 21 years back.
ISSN:0970-9290
1998-3603
DOI:10.4103/0970-9290.57366