Experimental pulpal Arthus allergy

Rabbits sensitized systemically to ovalbumin displayed skin reactions of the Arthus type and high titers of circulating antibodies. Their incisor pulp was removed at intervals after local challenge with 0.001 ml of 1 percent ovalbumin. Acute inflammatory lesions were demonstrated in the pulp by opti...

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Bibliographic Details
Published inOral surgery, oral medicine, oral pathology Vol. 50; no. 5; pp. 450 - 456
Main Authors Adamkiewicz, V.W., Peković, D.D.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.11.1980
Subjects
Animals
Arthus Reaction - immunology
Arthus Reaction - pathology
Dental Pulp - immunology
Dental Pulp - pathology
Dental Pulp - ultrastructure
Dentistry
Fluorescent Antibody Technique
Microscopy, Electron
Ovalbumin - immunology
Rabbits
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Summary:Rabbits sensitized systemically to ovalbumin displayed skin reactions of the Arthus type and high titers of circulating antibodies. Their incisor pulp was removed at intervals after local challenge with 0.001 ml of 1 percent ovalbumin. Acute inflammatory lesions were demonstrated in the pulp by optical and electron microscopy. Immunofluorescence revealed massive accumulations of antigen-antibody complexes in the lesions, confirming the presence of an Arthus type of allergy.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0030-4220
1878-2175
DOI:10.1016/S0030-4220(80)80014-4