Multiple Intramedullary Spinal Sarcoidosis: Case Report

• Published in: Surgical neurology Vol. 48; no. 5; pp. 522 - 526
• Main Authors: Chitoku, Shiro, Kawai, Shozo, Watabe, Yasuharu, Nishitani, Masaya, Fujimoto, Kenta, Otsuka, Hiroyuki, Fushimi, Hiroaki, Kotoh, Kiyoshi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.1997
• Subjects: corticosteroid therapy; Humans; intramedullary lesion; Male; Middle Aged; Sarcoidosis; spinal cord sarcoidosis; Spinal Diseases; Sarcoidosis; corticosteroid therapy; intramedullary lesion; spinal cord sarcoidosis
• ISSN: 0090-3019; 1879-3339
• DOI: 10.1016/S0090-3019(97)00170-5

Background According to past reported cases, spinal intramedullary sarcoidosis has the radiologic characteristics of a single enhanced lesion with cord swelling. However, it is difficult to make a diagnosis using only radiologic examinations. Including our case, 20 cases have been reported of intramedullary spinal sarcoidosis. Only six cases were diagnosed as primary spinal sarcoidosis. We present a rare case of multiple spinal intramedullary sarcoidosis without cord swelling. Case Description This 63 year-old man was afflicted with progressive paraparesis and numbness of the lower extremities. Magnetic resonance imaging showed intramedullary lesions without cord swelling. The patient underwent biopsy for diagnosis and the specimen showed a noncaseating granuloma mainly composed of epitheloid cells. Postoperative corticosteroid therapy was effective and the lesion disappeared 1 month after the operation. Conclusions Biopsy is a less invasive method and is useful for early diagnosis. Early diagnosis is important for spinal sarcoidosis so that high-dose corticosteroid therapy can be commenced while the lesion still has a good chance of being successfully treated.