Comparison of trabeculectomy and trabeculectomy with amniotic membrane transplantation in the same patient with bilateral glaucoma

• Published in: International journal of ophthalmology Vol. 6; no. 4; pp. 448 - 451
• Main Authors: Ji, Qing-Shan, Qi, Bing, Liu, Lian, Lao, Wei, Yang, Zhi-Hao, Wang, Gui-Fang, Yu, Guo-Cheng, Zhong, Jing-Xiang
• Format: Journal Article
• Language: English
• Published: China International Journal of Ophthalmology Press 2013; Press of International Journal of Ophthalmology (IJO PRESS)
• Subjects: amniotic; amniotic membrane transplantation; Clinical Research; glaucoma; membrane; trabeculectomy; transplantation; glaucoma; amniotic membrane transplantation; trabeculectomy
• ISSN: 2222-3959; 2227-4898
• DOI: 10.3980/j.issn.2222-3959.2013.04.07

AIM:To observe effects of trabeculectomy with amniotic membrane transplantation(AMT) in controlling postoperative intraocular pressure(IOP) in patients with medically uncontrolled glaucoma.·METHODS:This study included adult patients with requiring bilateral glaucoma surgery.Each patient underwent trabeculectomy(Non-AMT group) in one eye and with AMT(AMT group) in the other eye according to randomized principle.Success was defined as intraocular pressure(IOP) <21mmHg without any anti-glaucoma medications at 24 months follow-up.The two groups were compared in terms of IOP,complications and success rate.·RESULTS:Thirty-four eyes of 17 patients were investigated in this study.There was no statistically signifcant difference in pre-operative IOP between the two groups.The mean IOP was lower in AMT group compared with Non-AMT group on follow up months 12,18,and 24.Postoperative complications were more frequent in Non-AMT group(35.3%,6/17) compared with AMT group(5.9%,1/17).The success rate of surgery was88.2%(15/17) in Non-AMT group and 100%(17/17) in AMT group.·CONCLUSION:Trabeculectomy with AMT is an effective procedure to reduce IOP and complications,thereby improving surgical success rates.