Head-to-head comparison of SARS-CoV-2 antigen-detecting rapid test with self-collected nasal swab versus professional-collected nasopharyngeal swab

• Published in: The European respiratory journal Vol. 57; no. 4; p. 2003961
• Main Authors: Lindner, Andreas K, Nikolai, Olga, Kausch, Franka, Wintel, Mia, Hommes, Franziska, Gertler, Maximilian, Krüger, Lisa J, Gaeddert, Mary, Tobian, Frank, Lainati, Federica, Köppel, Lisa, Seybold, Joachim, Corman, Victor M, Drosten, Christian, Hofmann, Jörg, Sacks, Jilian A, Mockenhaupt, Frank P, Denkinger, Claudia M
• Format: Journal Article
• Language: English
• Published: England European Respiratory Society 01.04.2021
• Subjects: Agora; COVID-19 - diagnosis; COVID-19 Testing - methods; Humans; Nasopharynx - virology; SARS-CoV-2 - isolation & purification; Self-Testing; Specimen Handling
• ISSN: 0903-1936; 1399-3003
• DOI: 10.1183/13993003.03961-2020

A number of antigen-detecting rapid diagnostic tests (Ag-RDTs) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are now commercially available and can result in rapid decisions on patient care, isolation and contact tracing at the point of care [1]. Two Ag-RDTs using nasopharyngeal (NP) swab samples meet World Health Organization (WHO) targets and are now approved through the WHO Emergency Use Listing procedure [2–4]. Supervised nasal self-sampling is a reliable alternative to professional nasopharyngeal sampling using a WHO-listed SARS-CoV-2 antigen-detecting rapid test. Self-sampling and potentially patient self-testing may be a future use case. https://bit.ly/3mup0hS