The use of topical 5-fluorouracil in the treatment of genital condylomas

Topical 5-FU is indicated for therapy-resistant condylomas and for extensive untreated vulvar condylomas. It may be the treatment of choice for vaginal condylomas. Applications of 5-FU once weekly to the vagina and twice weekly to the vulva for 10 weeks appear to be as effective as continued regimen...

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Bibliographic Details
Published inObstetrics and gynecology clinics of North America Vol. 14; no. 2; p. 559
Main Author Krebs, H B
Format Journal Article
LanguageEnglish
Published United States 01.06.1987
Subjects
Administration, Topical
Combined Modality Therapy
Condylomata Acuminata - drug therapy
Condylomata Acuminata - prevention & control
Female
Fluorouracil - administration & dosage
Fluorouracil - pharmacology
Fluorouracil - therapeutic use
Genital Neoplasms, Female - drug therapy
Genital Neoplasms, Female - prevention & control
Humans
Laser Therapy
Neoplasm Recurrence, Local - prevention & control
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Summary:Topical 5-FU is indicated for therapy-resistant condylomas and for extensive untreated vulvar condylomas. It may be the treatment of choice for vaginal condylomas. Applications of 5-FU once weekly to the vagina and twice weekly to the vulva for 10 weeks appear to be as effective as continued regimens but are better tolerated. Perhaps the greatest value of 5-FU lies in the periodic application for prevention of recurrences of condylomas removed by surgical methods.
ISSN:0889-8545
DOI:10.1016/S0889-8545(21)00071-1