An automatic continuous flow method for the determination of antipolyamine antibodies in human sera

Latex particles with covalently bound polyamines were used to detect antipolyamine antibodies in human sera in manual and automated nephelometric assays. There was good correlation between the two assays though in the former aggregate size was measured after 24 h incubation whereas in the latter mon...

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Bibliographic Details
Published inJournal of immunological methods Vol. 33; no. 2; p. 159
Main Authors Ripoll, J P, Roch, A M, Quash, G A, Grange, J
Format Journal Article
LanguageEnglish
Published Netherlands 01.01.1980
Subjects
Animals
Antibody Specificity
Autoanalysis
Goats
Humans
Immune Sera - pharmacology
Immunologic Techniques - standards
Latex
Light
Microspheres
Polyamines - immunology
Scattering, Radiation
Time Factors
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Summary:Latex particles with covalently bound polyamines were used to detect antipolyamine antibodies in human sera in manual and automated nephelometric assays. There was good correlation between the two assays though in the former aggregate size was measured after 24 h incubation whereas in the latter monomer loss was determined after 1 h.
ISSN:0022-1759
1872-7905
DOI:10.1016/S0022-1759(80)80006-8