Magnesium supplement intake and C-reactive protein levels in adults
Previous research has indicated that dietary magnesium may be a key component in the association between diet and inflammation; however, the role of intake from magnesium supplements has not been elucidated. The objective of this study was to determine the likelihood of elevated C-reactive protein (...
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Published in | Nutrition research (New York, N.Y.) Vol. 26; no. 5; pp. 193 - 196 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
New York, NY
Elsevier Inc
01.05.2006
Elsevier Science |
Subjects | |
Online Access | Get full text |
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Summary: | Previous research has indicated that dietary magnesium may be a key component in the association between diet and inflammation; however, the role of intake from magnesium supplements has not been elucidated. The objective of this study was to determine the likelihood of elevated C-reactive protein (CRP) in people taking magnesium-containing supplements of 50 mg/d or more. We examined this issue in a study sample derived from the National Health and Nutrition Examination Survey 1999-2002, a nationally representative, survey of the civilian, noninstitutionalized population of the United States. Among US adults, 25.6% were taking a magnesium supplement of at least 50 mg daily. Only 21.9% of individuals not taking supplemental magnesium met or exceeded the recommended daily allowances (RDA) for magnesium intake compared with 60.2% of adults who were taking magnesium supplements. In adjusted logistic regression analyses, people whose total daily magnesium intake was below the RDA were significantly 40% more likely to have elevated CRP regardless of whether they were taking magnesium supplements (
P < .05). Among people with dietary magnesium intake less than 50% RDA, individuals taking magnesium supplements were 22% less likely to have elevated CRP. Magnesium supplement intake is associated with a lower likelihood of elevated CRP in people with low dietary magnesium intake. Prospective studies are needed to examine whether magnesium supplementation can reduce levels of CRP. |
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Bibliography: | http://dx.doi.org/10.1016/j.nutres.2006.05.001 |
ISSN: | 0271-5317 1879-0739 |
DOI: | 10.1016/j.nutres.2006.05.001 |