The use of surface spreading in the pachytene analysis of a human t (Y;17) reciprocal translocation

This paper describes a human Y;17 reciprocal translocation in an azoospermic male ascertained through infertility. Meiotic studies made on both air-dried and surface-spread preparations are reported in addition to a somatic chromosome analysis carried out by high resolution R-banding on pro-metaphas...

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Bibliographic Details
Published inCytogenetics and cell genetics Vol. 33; no. 4; p. 312
Main Authors Laurent, C, Chandley, A C, Dutrillaux, B, Speed, R M
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1982
Subjects
Chromosome Aberrations - pathology
Chromosome Disorders
Chromosomes - ultrastructure
Chromosomes, Human, 16-18
Humans
Infertility, Male - genetics
Infertility, Male - pathology
Male
Meiosis
Translocation, Genetic
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Summary:This paper describes a human Y;17 reciprocal translocation in an azoospermic male ascertained through infertility. Meiotic studies made on both air-dried and surface-spread preparations are reported in addition to a somatic chromosome analysis carried out by high resolution R-banding on pro-metaphase chromosomes. The possible cause of spermatogenic disturbance in Y-autosome heterozygotes is discussed.
ISSN:0301-0171
DOI:10.1159/000131777