Central corneal thickness measurements by ultrasound, Orbscan II, and Visante OCT after LASIK for myopia

To compare central corneal thickness measurements obtained with Orbscan II scanning slit topography, Visante optical coherence tomography (OCT), and ultrasound pachymetry in myopic eyes after LASIK. This retrospective study included 34 consecutive patients (68 eyes) who underwent LASIK for the corre...

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Published inJournal of refractive surgery (1995) Vol. 24; no. 4; pp. 361 - 365
Main Authors Cheng, Arthur C K, Rao, Srinivas K, Lau, Silvania, Leung, Chris K S, Lam, Dennis S C
Format Journal Article
LanguageEnglish
Published United States SLACK INCORPORATED 01.04.2008
Subjects
Accuracy
Acoustics
Agreements
Biometry
Cornea
Cornea - pathology
Corneal Topography - methods
Humans
Keratomileusis, Laser In Situ
Lasers, Excimer
Microscopy, Acoustic - methods
Myopia
Myopia - surgery
Postoperative Period
Regression analysis
Reproducibility of Results
Software
Tomography, Optical Coherence - methods
Ultrasonic imaging
Germany
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Summary:To compare central corneal thickness measurements obtained with Orbscan II scanning slit topography, Visante optical coherence tomography (OCT), and ultrasound pachymetry in myopic eyes after LASIK. This retrospective study included 34 consecutive patients (68 eyes) who underwent LASIK for the correction of myopia. Six months after surgery, central corneal thickness measurements were obtained using ultrasound pachymetry, Orbscan scanning slit topography, and Visante OCT. Data were analyzed using paired sample t test, Bland and Altman plot, and linear regression. Average postoperative central corneal thickness was 436.65+/-43.82 microm for ultrasound pachymetry, 422.84+/-51.04 microm for Orbscan (0.89 acoustic equivalent correction factor), and 422.26+/-42.46 microm for Visante. Compared to the ultrasound measurement, Orbscan and Visante measurements significantly underestimated the corneal thickness by 13.81+/-17.34 microm (P<.01) and 14.38+/-10.13 microm (P<.01), respectively. Both Orbscan and Visante OCT underestimated central corneal thickness compared to ultrasound pachymetry 6 months after LASIK, although measurements obtained with Visante OCT had better agreement and correlation with ultrasound pachymetry than with Orbscan.
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ISSN:1081-597X
1938-2391
DOI:10.3928/1081597x-20080401-08