The floppy infant: recent advances in the understanding of disorders affecting the neuromuscular junction

The clinician is often asked to evaluate the floppy infant. Numerous conditions that cause hypotonia in infancy are briefly outlined in this article. These conditions may affect the brain, spinal cord, or motor unit. Several disorders of neuromuscular transmission, including four distinct and recent...

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Bibliographic Details
Published inNeurologic clinics Vol. 8; no. 3; p. 715
Main Authors Gay, C T, Bodensteiner, J B
Format Journal Article
LanguageEnglish
Published United States 01.08.1990
Subjects
Brain - physiopathology
Humans
Infant
Muscle Hypotonia - physiopathology
Muscles - innervation
Neuromuscular Diseases - physiopathology
Neuromuscular Junction - physiopathology
Spinal Cord - physiopathology
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Summary:The clinician is often asked to evaluate the floppy infant. Numerous conditions that cause hypotonia in infancy are briefly outlined in this article. These conditions may affect the brain, spinal cord, or motor unit. Several disorders of neuromuscular transmission, including four distinct and recently described congenital myasthenic syndromes and infant botulism, are discussed thereafter.
ISSN:0733-8619
DOI:10.1016/S0733-8619(18)30344-X