A novel retrodihydrochalcone from the stem bark of Uvaria mocoli

• Published in: Phytochemistry (Oxford) Vol. 47; no. 7; pp. 1387 - 1391
• Main Authors: Fleischer, Theophilus C., Waigh, Roger D., Waterman, Peter G.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 1998; Elsevier
• Subjects: bark; Biochemistry & Molecular Biology; Biological and medical sciences; chalcones; chemical constituents of plants; Chemical constitution; chemical structure; Fundamental and applied biological sciences. Psychology; Life Sciences & Biomedicine; nuclear magnetic resonance spectroscopy; plant extracts; Plant physiology and development; Plant Sciences; Science & Technology; spectral analysis; stems; Uvaria; Ghana; chalcones; dihydrochalcones; Annonaceae; Uvaria mocoli; oxoaporphine alkaloids; flavanones; RETROCHALCONE; SESQUITERPENE; FLAVONOIDS; GENUS UVARIA; CHEMISTRY; PLANTS; ANGOLENSIS; CONSTITUENTS; Alkaloid; Molecular structure; Dicotyledones; Angiospermae; Bark; Isolation; Spermatophyta; Flavonoid; Chalcone; Stem
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/S0031-9422(98)80009-5

A new retrodihydrochalcone has been isolated from the stem bark of Uvaria mocoli (Annonaceae) and identified as 2-hydroxy-4,5,6-trimethoxydihydrochalcone. Investigation of the ethyl acetate extract of the stem bark of Uvaria mocoli resulted in the isolation of the novel retrodihydrochalcone 2-hydroxy-4,5,6-trimethoxydihydrochalcone together with the known flavonoids 2′-hydroxy-4′,6′-dimethoxychalcone, 2′-hydroxy-4′,5′,6′-trimethoxychalcone, 5,7-dimethoxyflavanone and 5,7,8-trimethoxyflavanone, the oxoaporphines lysicamine, liriodenine and isomoschatoline, benzoic acid and a mixture of sitosterol and stigmasterol. All the compounds were identified by analysis of their spectral data.