Chromatin Variants Reveal the Genetic Determinants of Oncogenesis in Breast Cancer

Breast cancer presents as multiple distinct disease entities. Each tumor harbors diverse cell populations defining a phenotypic heterogeneity that impinges on our ability to treat patients. To date, efforts mainly focused on genetic variants to find drivers of inter- and intratumor phenotypic hetero...

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Bibliographic Details
Published inCold Spring Harbor perspectives in medicine Vol. 12; no. 10; p. a041322
Main Authors Bahl, Shalini, Carroll, Jason S, Lupien, Mathieu
Format Journal Article
LanguageEnglish
Published United States Cold Spring Harbor Laboratory Press 01.10.2022
Subjects
Carcinogenesis
Cell Transformation, Neoplastic
Chromatin - genetics
Genetic Heterogeneity
Humans
Neoplasms
Precision Medicine
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