Pharmaceutical development and specification of stereoisomers

The pharmaceutical development of chiral drugs requires the activities of many different research and development groups. Guidelines which help to coordinate the activities of these groups and assist in the successful development of compounds with either single or multiple chiral centers are outline...

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Bibliographic Details
Published inJournal of pharmaceutical and biomedical analysis Vol. 17; no. 6; pp. 917 - 924
Main Authors Williams, Reed C., Riley, Christopher M., Sigvardson, Kenneth W., Fortunak, Joseph, Ma, Phillip, Nicolas, Edgar C., Unger, Steven E., Krahn, David F., Bremner, Stephen L.
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 01.09.1998
Subjects
Chiral analysis
Clinical Trials as Topic
Drug Evaluation - methods
Drug Evaluation - standards
Enantiomer
Guidelines as Topic - standards
Humans
Pharmaceutical
Specification
Stereoisomerism
Stereoisomers
Terminology as Topic
Stereoisomers
Chiral analysis
Specification
Pharmaceutical
Enantiomer
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Summary:The pharmaceutical development of chiral drugs requires the activities of many different research and development groups. Guidelines which help to coordinate the activities of these groups and assist in the successful development of compounds with either single or multiple chiral centers are outlined and discussed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0731-7085
1873-264X
DOI:10.1016/S0731-7085(98)00059-4