Celiac Disease: Extraintestinal Manifestations and Associated Conditions

• Published in: Journal of clinical gastroenterology Vol. 54; no. 1; p. 8
• Main Authors: Therrien, Amelie, Kelly, Ciaran P, Silvester, Jocelyn A
• Format: Journal Article
• Language: English
• Published: United States 01.01.2020
• Subjects: Celiac Disease - complications; Celiac Disease - diagnosis; Celiac Disease - diet therapy; Delayed Diagnosis; Diet, Gluten-Free; Eye Diseases - diagnosis; Eye Diseases - etiology; Gastrointestinal Diseases - diagnosis; Gastrointestinal Diseases - etiology; Humans; Malnutrition - diagnosis; Malnutrition - etiology; Mental Disorders - diagnosis; Mental Disorders - etiology; Mouth Diseases - diagnosis; Mouth Diseases - etiology; Musculoskeletal Diseases - diagnosis; Musculoskeletal Diseases - etiology; Nervous System Diseases - diagnosis; Nervous System Diseases - etiology; Skin Diseases - diagnosis; Skin Diseases - etiology; Symptom Assessment
• ISSN: 1539-2031
• DOI: 10.1097/MCG.0000000000001267

Celiac disease is a common form of enteropathy with frequent extraintestinal manifestations (EIM). Misrecognition of these presentations may lead to significant delays in diagnosis. Any organ may be involved, either through an immune/inflammatory phenomenon, or nutritional deficiencies. Some EIM, such as gluten ataxia, may be irreversible if left untreated, but most will improve with a gluten-free diet. Knowledge of the various EIM, as well as the associated conditions which do not improve on a gluten-free diet, will avoid delays in the diagnosis and management of celiac disease and associated manifestations.