Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B1
A total of 480 one-day-old AA broiler chicks were randomly allocated to one of four treatments in a 2 × 2 factorial to investigate the effects of tannic acid (TA) on growth performance, relative organ weight, antioxidant capacity, and intestinal health in broilers dietary exposed to aflatoxin B 1 (A...
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Published in | Frontiers in veterinary science Vol. 9; p. 1037046 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Frontiers Media S.A
21.10.2022
|
Subjects | |
Online Access | Get full text |
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Summary: | A total of 480 one-day-old AA broiler chicks were randomly allocated to one of four treatments in a 2 × 2 factorial to investigate the effects of tannic acid (TA) on growth performance, relative organ weight, antioxidant capacity, and intestinal health in broilers dietary exposed to aflatoxin B
1
(AFB
1
). Treatments were as follows: (1) CON, control diet; (2) TA, CON + 250 mg/kg TA; (3) AFB
1
, CON + 500 μg/kg AFB
1
; and (4) TA+AFB
1
, CON + 250 mg/kg TA + 500 μg/kg AFB
1
. There were 10 replicate pens with 12 broilers per replicate. Dietary AFB
1
challenge increased the feed conversion ratio during days 1 to 21 (
P
< 0.05). The TA in the diet did not show significant effects on the growth performance of broilers during the whole experiment period (
P
> 0.05). The liver and kidney relative weight was increased in the AF challenge groups compared with the CON (
P
< 0.05). The addition of TA could alleviate the relative weight increase of liver and kidney caused by AFB
1
(
P
< 0.05). Broilers fed the AFB
1
diets had lower activity of glutathione peroxidase, catalase, total superoxide dismutase, S-transferase, and total antioxidant capacity in plasma, liver and jejunum, and greater malondialdehyde content (
P
< 0.05). Dietary supplemented with 250 mg/kg TA increased the activities of antioxidative enzymes, and decreased malondialdehyde content (
P
< 0.05). In addition, AFB
1
significantly reduced the villus height and crypt depth ratio in the ileum on day 42 (
P
< 0.05). In conclusion, supplementation with 250 mg/kg TA could partially protect the antioxidant capacity and prevent the enlargement of liver in broilers dietary challenged with 500 μg/kg AFB
1
. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Reviewed by: Xi Wang, Southwest Minzu University, China; Muhammad Saeed, Northwest A&F University, China; Dafei Yin, Shenyang Agricultural University, China These authors have contributed equally to this work This article was submitted to Animal Nutrition and Metabolism, a section of the journal Frontiers in Veterinary Science Edited by: Wen-Chao Liu, Guangdong Ocean University, China |
ISSN: | 2297-1769 2297-1769 |
DOI: | 10.3389/fvets.2022.1037046 |