First report from the International Evaluation of Endoscopic classification Japan NBI Expert Team: International multicenter web trial

• Published in: Digestive endoscopy Vol. 36; no. 5; pp. 591 - 599
• Main Authors: Sakamoto, Taku, Dekker, Evelien, Pioche, Mathieu, Probst, Andreas, Ponchon, Thierry, Messmann, Helmut, Dinis‐Ribeiro, Mario, Matsuda, Takahisa, Ikematsu, Hiroaki, Saito, Shoichi, Wada, Yoshiki, Oka, Shiro, Sano, Yasushi, Fujishiro, Mitsuhiro, Murakami, Yoshitaka, Ishikawa, Hideki, Inoue, Haruhiro, Tanaka, Shinji, Tajiri, Hisao, Nagl, Sandra, Kaminski, Michal F., Panarese, Alba, Pellisé, Maria, Puig, Ignasi, Arnaud, Lemmers, Kuvaev, Roman, Matsui, Takanori, Kobashi, Ryoichiro, Ebigbo, Alanna, Höfer, Susanne, Quintero, Enrique, van Leerdam, M. E., Houwen, Britt B. S. L., Suzuki, Noriko, Friederike, Prinz, Dewint, Pieter, Jérémie, Jacques, Taniguchi, Yasuhiro, Shimakura, Akane, Hida, Emiko, Muroi, Koichi, Suzuki, Tomohiko, Suzuki, Takahiro, Hirose, Takashi, Sasabe, Maasa, Watanabe, Takashi, Römmele, Christoph, Bisschops, Raf, Nakamura, Takahiko, Tani, Yasuhiro, Yamamoto, Kei, Manabe, Taku, Dietrich, Christian, Bastiaansen, Barbara, Fockens, Paul, Hazewinkel, Yark, Mitsui, Tomohiro, Ishida, Satoshi, Shimada, Seitaro, Suwa, Tetsuya, Shiina, Osamu, Kuroki, Takanori, Morita, Yuriko, Nakatani, Shinya, Kikuchi, Kazuo, Gocho, Toshihiko, Wagner, Andrej, Cortas, George Adel, Koizumi, Akio, Horiuchi, Hideka, Arnout van Hattem, W., Kakushima, Naomi, Kobayashi, Sakurako, Yamada, Daiki, Watanabe, Satoshi, Kawasaki, Sho, Ida, Tomohiro, Honda, Hidehito, Nakajima, Keisuke, Nemoto, Mao, Kusunoki, Kenichi, Bustamante‐Balén, Marco, Monino, Laurent, Jakobs, Ralf, Repici, Alessandro, Kashin, Sergey, Jover, Rodrigo, Berr, Frieder, Neumann, Helmut, Koga, Erika, Takehara, Sayuri, Miyagi, Taiga, Matt, Rutter, Onodera, Sho, Sawada, Atsushi, Ozeki, Yuichiro, Parra‐Blanco, Adolfo, Haji, Amyn, Ribeiro, Mário Dinis, Saurin, J. C.
• Format: Journal Article
• Language: English
• Published: Australia 01.05.2024
• Subjects: Colonoscopy - methods; Colorectal Neoplasms - diagnosis; Colorectal Neoplasms - diagnostic imaging; Colorectal Neoplasms - pathology; ESGE (European Society of Gastrointestinal Endoscopy); E‐test; Humans; Japan; JGES (Japan Gastroenterological Endoscopy Society); JNET (Japan NBI Expert Team); Narrow Band Imaging; narrow‐band imaging (NBI); Reproducibility of Results; Sensitivity and Specificity; Japan; JNET (Japan NBI Expert Team); JGES (Japan Gastroenterological Endoscopy Society); E‐test; narrow‐band imaging (NBI); ESGE (European Society of Gastrointestinal Endoscopy)
• ISSN: 0915-5635; 1443-1661
• DOI: 10.1111/den.14682

Objectives Narrow‐band imaging (NBI) contributes to real‐time optical diagnosis and classification of colorectal lesions. The Japan NBI Expert Team (JNET) was introduced in 2011. The aim of this study was to explore the diagnostic accuracy of JNET when applied by European and Japanese endoscopists not familiar with this classification. Methods This study was conducted by 36 European Society of Gastrointestinal Endoscopy (ESGE) and 49 Japan Gastroenterological Endoscopy Society (JGES) non‐JNET endoscopists using still images of 150 lesions. For each lesion, nonmagnified white‐light, nonmagnified NBI, and magnified NBI images were presented. In the magnified NBI, the evaluation area was designated by region of interest (ROI). The endoscopists scored histological prediction for each lesion. Results In ESGE members, the sensitivity, specificity, and accuracy were respectively 73.3%, 94.7%, and 93.0% for JNET Type 1; 53.0%, 64.9%, and 62.1% for Type 2A; 43.9%, 67.7%, and 55.1% for Type 2B; and 38.1%, 93.7%, and 85.1% for Type 3. When Type 2B and 3 were considered as one category of cancer, the sensitivity, specificity, and accuracy for differentiating high‐grade dysplasia and cancer from the others were 59.9%, 72.5%, and 63.8%, respectively. These trends were the same for JGES endoscopists. Conclusion The diagnostic accuracy of the JNET classification was similar between ESGE and JGES and considered to be sufficient for JNET Type 1. On the other hand, the accuracy for Types 2 and 3 is not sufficient; however, JNET 2B lesions should be resected en bloc due to the risk of cancers and JNET 3 can be treated by surgery due to its high specificity.