Neuroendocrine tumors of the gynecologic tract update

•WHO has updated NET classifications in order to simplify terminology across NETs.•Treatment recommendations for cervical NEC have been updated and outlined.•Hypercalcemic type ovarian NECs are no longer considered true NENs.•Treatment for most gynecologic NECs/NENs is derived from experience with o...

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Bibliographic Details
Published inGynecologic oncology Vol. 162; no. 1; pp. 210 - 219
Main Authors Winer, I., Kim, C., Gehrig, P.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.07.2021
Subjects
Clinical Trials, Phase II as Topic
Female
Genital Neoplasms, Female - classification
Genital Neoplasms, Female - diagnosis
Genital Neoplasms, Female - therapy
Humans
Neuroendocrine tumors
Neuroendocrine Tumors - classification
Neuroendocrine Tumors - diagnosis
Neuroendocrine Tumors - therapy
Neuroendocrine tumors
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Summary:•WHO has updated NET classifications in order to simplify terminology across NETs.•Treatment recommendations for cervical NEC have been updated and outlined.•Hypercalcemic type ovarian NECs are no longer considered true NENs.•Treatment for most gynecologic NECs/NENs is derived from experience with other NETs.•Clinical trials are needed to improve outcomes in patients with NETs.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0090-8258
1095-6859
DOI:10.1016/j.ygyno.2021.04.039