Different antibody response against Candida albicans cell wall antigens in cervicovaginal secretions of patients with vulvovaginal candidiasis

Vaginal washings from 118 women were investigated by means of immunofluorescence for the presence of antibodies against Candida albicans. A significantly (p less than 0.02) higher antibody titer was found in the samples from patients with clinically evident vulvovaginal candidiasis. Vaginal secretio...

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Published inGynecologic and obstetric investigation Vol. 30; no. 3; p. 174
Main Authors Schneider, J, Vicandi, J, Regulez, P, Quindós, G, Pontón, J, Cisterna, R
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1990
Subjects
Antibodies, Fungal - immunology
Antigens, Fungal - immunology
Blotting, Western
Candidiasis, Vulvovaginal - immunology
Female
Fluorescent Antibody Technique
Humans
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Summary:Vaginal washings from 118 women were investigated by means of immunofluorescence for the presence of antibodies against Candida albicans. A significantly (p less than 0.02) higher antibody titer was found in the samples from patients with clinically evident vulvovaginal candidiasis. Vaginal secretions from those patients with a positive culture for C. albicans were assayed by means of Western blotting. A distinct band pattern was found in the group of patients with a positive culture and the classical clinical picture of C. albicans vulvovaginitis.
ISSN:0378-7346
DOI:10.1159/000293258