Fluid restriction during running increases GI permeability

• Published in: International journal of sports medicine Vol. 29; no. 3; p. 194
• Main Authors: Lambert, G P, Lang, J, Bull, A, Pfeifer, P C, Eckerson, J, Moore, G, Lanspa, S, O'Brien, J
• Format: Journal Article
• Language: English
• Published: Germany 01.03.2008
• Subjects: Adult; Double-Blind Method; Duodenum - metabolism; Female; Gastrointestinal Agents - pharmacokinetics; Gastrointestinal Agents - urine; Glucose Solution, Hypertonic - pharmacokinetics; Humans; Intestinal Absorption - physiology; Intestine, Small - metabolism; Lactulose - pharmacokinetics; Lactulose - urine; Male; Permeability; Rest - physiology; Rhamnose - pharmacokinetics; Rhamnose - urine; Running - physiology; Sucrose - pharmacokinetics; Sucrose - urine; Sweetening Agents - pharmacokinetics; Water Deprivation
• ISSN: 0172-4622
• DOI: 10.1055/s-2007-965163

The purpose of this study was to determine gastrointestinal (GI) permeability during prolonged treadmill running (60 min at 70 % V.O2max) with and without fluid intake (3 ml/kg body mass/10 min). Twenty runners (11 males, 9 females; age = 22 +/- 3 (SD) yrs; mean V.O2max = 55.7 +/- 5.0 ml/kg/min) com...