Presence of ribonucleotide sequences complementary to rous sarcoma virus (RSV) RNA in chicken cells infected with RSV

RNA-RNA molecular hybridization between [ 125I]RNA from Rous sarcoma virus virions and RNAs isolated from various subcellular fractions, i.e. nuclei, mitochondria, free and membrane-bound polyribosomes, from tumors induced by RSV in chickens resulted in the formation of RNAase-resistant hybrids only...

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Bibliographic Details
Published inCancer letters Vol. 2; no. 6; pp. 349 - 354
Main Authors Shaposhnikov, Jacob D., Ratovitski, Edward A., Kuznetsov, Oleg K.
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.05.1977
Subjects
Animals
Avian Sarcoma Viruses - metabolism
Base Sequence
Chickens
Mitochondria - metabolism
Nucleic Acid Hybridization
Polyribosomes - metabolism
RNA, Neoplasm - metabolism
RNA, Viral - metabolism
Sarcoma, Avian - metabolism
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Summary:RNA-RNA molecular hybridization between [ 125I]RNA from Rous sarcoma virus virions and RNAs isolated from various subcellular fractions, i.e. nuclei, mitochondria, free and membrane-bound polyribosomes, from tumors induced by RSV in chickens resulted in the formation of RNAase-resistant hybrids only with the RNA of mitochondria and membrane-bound polysomes. The origin of complementary regions in the RNAs from these organelles is discussed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0304-3835
1872-7980
DOI:10.1016/S0304-3835(77)80016-5