Vitamin a action on hepatic cholesterol biosynthesis

Vitamin A action on hepatic cholesterol biosynthesis in the rat animal model is nonconsistent and complex. Not only does Vitamin A enhance and depress cholesterol synthesis but the action of this nutrient is influenced by several factors such as: vitamin A status of the animal; form of vitamin A use...

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Bibliographic Details
Published inNutrition research (New York, N.Y.) Vol. 4; no. 1; pp. 137 - 144
Main Authors Ott, Dana B., Lachance, Paul A.
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 1984
Elsevier Science
Subjects
Biological and medical sciences
cholesterol
Fundamental and applied biological sciences. Psychology
hepatic
Liver. Bile. Biliary tracts
metabolism
retinoids
Vertebrates: digestive system
vitamin A
cholesterol
hepatic
metabolism
vitamin A
retinoids
Vertebrata
Mammalia
Rat
Liver
Rodentia
Biosynthesis
Metabolism
Cholesterol
Retinol
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Summary:Vitamin A action on hepatic cholesterol biosynthesis in the rat animal model is nonconsistent and complex. Not only does Vitamin A enhance and depress cholesterol synthesis but the action of this nutrient is influenced by several factors such as: vitamin A status of the animal; form of vitamin A used; vitamin A metabolites; animal feeding regimen; substrate flux; and supernatant protein factors.
Bibliography:S20
S
ISSN:0271-5317
1879-0739
DOI:10.1016/S0271-5317(84)80144-X