Kangaroo endogenous retrovirus (KERV) forms megasatellite DNA with a simple repetition pattern in which the provirus structure is retained

• Published in: Virology (New York, N.Y.) Vol. 586; pp. 56 - 66
• Main Authors: Koga, Akihiko, Nishihara, Hidenori, Tanabe, Hideyuki, Tanaka, Rieko, Kayano, Rika, Matsumoto, Shinya, Endo, Taiki, Srikulnath, Kornsorn, O'Neill, Rachel J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2023
• Subjects: Amplification; Centromere; Elongation; Evolution; Homologous recombination; Host genome; Marsupial; Pairing slippage; Tandem duplication; Amplification; Host genome; Centromere; Marsupial; Homologous recombination; Tandem duplication; Evolution; Elongation; Pairing slippage

The kangaroo endogenous retrovirus (KERV) was previously reported to have undergone a rapid copy number increase in the red-necked wallaby; however, the mode of amplification was left to be clarified. The present study revealed that the long terminal repeat (LTR) (0.6 kb) and internal region (2.0 kb...