Simulation studies of biomagnetic computed tomography (current flow identification)

Simulation studies were performed on phantom models of electrical sources. As a first step toward the development of an imaging algorithm, the simplified problem of identifying the shape and direction of current flow in a planar surface was addressed. The problem was formulated by identifying a spac...

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Bibliographic Details
Published inIEEE transactions on biomedical engineering Vol. 40; no. 4; pp. 317 - 322
Main Authors Ramon, C., Mayer, M.G., Nelson, A.C., Spelman, F.A., Lamping, J.
Format Journal Article
LanguageEnglish
Published New York, NY IEEE 01.04.1993
Institute of Electrical and Electronics Engineers
Subjects
Biological and medical sciences
Biomagnetics
Computational modeling
Computed tomography
Computer Simulation
Humans
Image Processing, Computer-Assisted - methods
Image reconstruction
Image sampling
Image segmentation
Imaging phantoms
Investigative techniques, diagnostic techniques (general aspects)
Magnetic fields
Magnetics
Mathematics
Medical sciences
Miscellaneous. Technology
Models, Theoretical
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Shape
Surface reconstruction
Tomography - methods
Tomography - standards
Reconstruction
Radiodiagnosis
Simulation
Distribution
Non invasive method
Signal processing
Exploration
Medical imagery
Computerized axial tomography
Technique
Magnetic field
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Summary:Simulation studies were performed on phantom models of electrical sources. As a first step toward the development of an imaging algorithm, the simplified problem of identifying the shape and direction of current flow in a planar surface was addressed. The problem was formulated by identifying a space in which the image was to be reconstructed. The space was segmented into a grid. Each grid space represented a current element. The magnetic field at a sampling point due to the current elements was computed using the Biot-Savart law. Since there were many more current elements than sample points, the problem was underdetermined and had an uncountable number of solutions. The projection theorem was used to define an analytic solution for the magnitude and orientation of the current elements in the grid space. The accuracy of the resulting image was determined by comparing it with the known location of the sources shows that shape of the filamentary current flow can be imaged with this technique. The resolution of images based on the sampling of the field, number of voxels in the reconstruction space, and noise is also analyzed.< >
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ISSN:0018-9294
1558-2531
DOI:10.1109/10.222323