Cystinuria: Effect of D-Penicillamine on Plasma and Urinary Cystine Concentrations
Administration of penicillamine reduced the concentration of cystine in the plasma and urine of patients with cystinuria; renal clearance of cystine, lysine, and arginine remained unchanged. Cysteine-penicillamine disulfide and penicillamine disulfide were detected in the plasma.
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Published in | Science (American Association for the Advancement of Science) Vol. 147; no. 3664; pp. 1459 - 1460 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
United States
American Association for the Advancement of Science
19.03.1965
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Subjects | |
Online Access | Get full text |
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Summary: | Administration of penicillamine reduced the concentration of cystine in the plasma and urine of patients with cystinuria; renal clearance of cystine, lysine, and arginine remained unchanged. Cysteine-penicillamine disulfide and penicillamine disulfide were detected in the plasma. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0036-8075 1095-9203 |
DOI: | 10.1126/science.147.3664.1459 |