The contentious relationship between artificial sweeteners and cardiovascular health

Sweet has always been a fundamental human taste, and while glucose and other kinds of sugar are our primary energy sources, they can also have detrimental effects on health, including weight gain, obesity, cardiovascular diseases, diabetes, and other metabolic diseases. Artificial sweeteners (AS), i...

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Published inThe Egyptian journal of internal medicine Vol. 35; no. 1; pp. 43 - 6
Main Authors Singh, Sandeep, Kohli, Aditya, Trivedi, Stuti, Kanagala, Sai Gautham, Anamika, F. N. U., Garg, Nikita, Patel, Meet A., Munjal, Ripudaman Singh, Jain, Rohit
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 20.06.2023
Springer Nature B.V
SpringerOpen
Subjects
Amino acids
Artificial sweeteners
Aspartame
Atherosclerosis
Atrial fibrillation
Blood pressure
Calories
Cardiac arrhythmia
Cardiovascular disease
Cardiovascular health
Cardiovascular system
Coronary vessels
Diabetes
FDA approval
Food additives
Heart
Hypertension
Internal Medicine
Medicine
Medicine & Public Health
Metabolic syndrome
Microbiota
Obesity
Oxidative stress
Potassium
Proteins
Review
Saccharin
Senescence
Vein & artery diseases
Aspartame
Artificial sweeteners
Saccharin
Cardiovascular health
Atrial fibrillation
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Summary:Sweet has always been a fundamental human taste, and while glucose and other kinds of sugar are our primary energy sources, they can also have detrimental effects on health, including weight gain, obesity, cardiovascular diseases, diabetes, and other metabolic diseases. Artificial sweeteners (AS), introduced as sugar substitutes, are a group of chemical compounds that attribute sweetness with almost zero calories and are considered safe for consumption by the Food and Drug Administration (FDA). Although they may help restrict the daily caloric intake of sugar to less than 10% of the daily caloric intake, there are still questions about the long-term safety of AS. A higher risk of hypertension, insulin resistance, high blood sugar, abdominal obesity, and dyslipidemia has been linked to AS. The effect of AS on the cardiovascular system is still unclear, and further research is required. This review examines the potential mechanism of how artificial sweeteners cause cardiovascular diseases.
ISSN:2090-9098
1110-7782
2090-9098
DOI:10.1186/s43162-023-00232-1