Fibrinolysis and antifibrinolytic drugs in the growth and spread of tumours

• Published in: Cancer treatment reviews Vol. 4; no. 3; pp. 213 - 217
• Main Author: Peterson, Hans-Inge
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.09.1977
• Subjects: Animals; Antifibrinolytic Agents - therapeutic use; Fibrin - metabolism; Fibrinolysis; Humans; Neoplasm Metastasis - drug therapy; Neoplasms - blood; Neoplasms - drug therapy; Neoplasms - physiopathology; Neoplastic Cells, Circulating; Plasminogen Activators - secretion

In the last few years increased release of fibrinolytic enzymes from malignant cells has been observed, but the significance of this property in relation to malignant growth is still not fully understood. Antifibrinolytic drugs decrease the growth rate of some experimental tumours and might have a s...