The secretion of cerebrospinal fluid

A critical review of the methods for the study of cerebrospinal fluid formation (CSF) is presented and the information obtained from these methods and from the effect of metabolic inhibitors is discussed. The models by which epithelia secrete fluid are briefly reviewed in relation to morphology, rec...

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Bibliographic Details
Published inExperimental eye research Vol. 25; pp. 127 - 148
Main Authors Segal, M.B., Pollay, M.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 1977
Subjects
Adenosine Triphosphatases - metabolism
Animals
Antimetabolites - pharmacology
Biological Transport, Active - drug effects
Cerebrospinal Fluid - metabolism
Choroid Plexus - metabolism
Choroid Plexus - ultrastructure
Electric Conductivity
Epithelium - metabolism
Osmolar Concentration
Rabbits
Secretory Rate - drug effects
Sodium - metabolism
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Summary:A critical review of the methods for the study of cerebrospinal fluid formation (CSF) is presented and the information obtained from these methods and from the effect of metabolic inhibitors is discussed. The models by which epithelia secrete fluid are briefly reviewed in relation to morphology, recent junctional classification and physiological observations. The application of these models to CSF secretion is correlated with recent morphological findings and a new tentative model of the secretion mechanism is postulated.
ISSN:0014-4835
1096-0007
DOI:10.1016/S0014-4835(77)80012-2