Enhanced MR neurography of the lumbosacral plexus with robust vascular suppression and improved delineation of its small branches

• Published in: European journal of radiology Vol. 129; p. 109128
• Main Authors: Zhang, Youlai, Kong, Xiangchuang, Zhao, Qian, Liu, Xi, Gu, Yudong, Xu, Lei
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.08.2020
• Subjects: Adult; Contrast Media; Female; Gadolinium; Humans; Image Enhancement - methods; Image Processing, Computer-Assisted - methods; Imaging, Three-Dimensional - methods; Lumbosacral plexus; Lumbosacral Plexus - diagnostic imaging; Lumbosacral Plexus - injuries; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Peripheral Nervous System Diseases - diagnostic imaging; Retrospective Studies; Signal-To-Noise Ratio; CNR; MRN; LSP; Lumbosacral plexus; Gadolinium; STIR; CR; SPACE; CT; 3D; Magnetic resonance imaging; MIP; SNR; EMG; Contrast media
• ISSN: 0720-048X; 1872-7727
• DOI: 10.1016/j.ejrad.2020.109128

•Enhanced MRN provides superior vascular suppression in assessing LSP.•Enhanced MRN demonstrates increased conspicuity of small branches of LSP.•Enhanced MRN may be of great value for making therapeutic-decisions in LSP injuries. To evaluate whether gadolinium enhanced 3D SPACE STIR sequence technique increases the visualization of the lumbosacral plexus (LSP) and its small branches. A retrospective study was performed on 24 patients who had underwent 3D SPACE STIR sequences scan with and without the administration of gadolinium contrast. In this study, we focused on the healthy sides of the LSP and its branches in each patient. The contrast ratio (CR), contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) were objectively calculated by two experienced radiologists. The subjective visualization scores of the branches that were vitally important to therapeutic decision-making including femoral nerves, obturator nerves, lumbosacral trunks, superior gluteal and extra-pelvic sciatic nerves, were assessed using post-processing images. Of the 24 subjects, all LSP nerve roots, femoral nerves, lumbosacral trunks and sciatic nerves were illustrated on both contrast-enhanced and non-contrast images. The enhanced images were found to have higher nerve to vein CNRs compared to non-contrast images. Compared to non-contrast images, the CRs of nerves versus surrounding fat tissues, bones, veins and muscles were improved in contrast-enhanced images, while the SNRs were better but not significantly so. Targeted maximum intensity projection (MIP) nerves including femoral, obturator, superior gluteal and extra-pelvic sciatic nerves obtained significantly higher subjective scores when gadolinium was administered. The gadolinium enhanced 3D SPACE STIR sequence provided superior vascular suppression, resulting in increased conspicuity of LSP and its small branches. Altogether, this shows great potential for therapeutic decision-making in traumatic LSP lesions cases.