Antioxidant Activity of Marine Algal Polyphenolic Compounds: A Mechanistic Approach

• Published in: Journal of medicinal food Vol. 19; no. 7; p. 615
• Main Authors: Fernando, I P Shanura, Kim, Misook, Son, Kwang-Tae, Jeong, Yoonhwa, Jeon, You-Jin
• Format: Journal Article
• Language: English
• Published: United States 01.07.2016
• Subjects: Antioxidants; Cosmetics; Flavonoids; Food Technology; Halogens; Health Promotion; Molecular Structure; Polyphenols - chemistry; Polyphenols - pharmacology; Reactive Oxygen Species; Seaweed - chemistry; Structure-Activity Relationship; Tannins; Technology, Pharmaceutical; ROS; phenolic acids; seaweed; flavonoids; radical scavenging mechanism; halogenated phenolic compounds; phlorotannins
• ISSN: 1557-7600
• DOI: 10.1089/jmf.2016.3706

Polyphenolic compounds isolated from marine algae exhibit a broad spectrum of beneficial biological properties, including antioxidant, anticancer, antimicrobial, anti-inflammatory, and antidiabetic activities, along with several other bioactivities centered on their antioxidant properties. Consequently, polyphenolic compounds are increasingly being investigated for their potential use in food, cosmetic, and pharmaceutical applications. The antioxidant activities of these compounds have been explored widely through experimental studies. Nonetheless, a theoretical understanding of the structural and electronic properties could broaden research perspectives, leading to the identification and synthesis of efficient structural analogs with prophylactic uses. This review briefly summarizes the current state of knowledge regarding antioxidant polyphenolic compounds in marine algae with an attempt to describe the structure-activity relationship.