Carbon Coating on Surface of PVC Blood Bags

Abstract In this work, we studied the effect of a carbon coating created on the surface of a polyvinyl chloride blood storage bags on protein adsorption, cell culture proliferation, and on whole blood leukocytes. Based on the results obtained, it can be assumed that the preservation of leukocytes is...

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Bibliographic Details
Published inJournal of physics. Conference series Vol. 1945; no. 1; pp. 12068 - 12073
Main Authors Chudinov, V S, Shardakov, I N
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 01.06.2021
Subjects
Bags
Carbon
Cell adhesion
Coating effects
Leukocytes
Physics
Polyvinyl chloride
Protein adsorption
Proteins
Storage containers
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Summary:Abstract In this work, we studied the effect of a carbon coating created on the surface of a polyvinyl chloride blood storage bags on protein adsorption, cell culture proliferation, and on whole blood leukocytes. Based on the results obtained, it can be assumed that the preservation of leukocytes is more effective in the blood storage bags treated by the ion-plasma method, in comparison with the untreated one. The adhesion of blood cells occurs on the carbon coating of the plasma-treated surface of the blood storage bags. This can be eliminated by preliminary application of proteins that prevent cell adhesion on the walls of the blood storage bags.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1945/1/012068