Effects of patient age, pH of cerebrospinal fluid, and vasopressors on onset and duration of spinal anesthesia

Two hundred twenty-two spinal anesthesias were administered with 10 mg. of tetracaine and 1 ml. of 10 percent dextrose to investigate the effects of vasopressors, patients age, and pH of cerebrospinal fluid on the onset and duration of spinal anesthesia. Neither the differences in overall age, cereb...

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Bibliographic Details
Published inAnesthesia and analgesia Vol. 54; no. 4; pp. 455 - 458
Main Authors Park, W Y, Balingit, P E, Macnamara, T E
Format Journal Article
LanguageEnglish
Published United States 01.07.1975
Subjects
Age Factors
Anesthesia, Spinal
Atropine
Cerebrospinal Fluid
Diazepam
Epinephrine - pharmacology
Humans
Hydrogen-Ion Concentration
Middle Aged
Pentobarbital
Phenylephrine - pharmacology
Preanesthetic Medication
Tetracaine
Time Factors
Vasoconstrictor Agents - pharmacology
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Summary:Two hundred twenty-two spinal anesthesias were administered with 10 mg. of tetracaine and 1 ml. of 10 percent dextrose to investigate the effects of vasopressors, patients age, and pH of cerebrospinal fluid on the onset and duration of spinal anesthesia. Neither the differences in overall age, cerebrospinal fluid pH, nor the addition of vasopressors had any significant effect on onset. Duration, however, was significantly prolonged by the addition of vasopressors, 53 percent prolongation by 0.2 mg. of epinephrine and 72 percent prolongation by 2 mg. of phenylephrine.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0003-2999
DOI:10.1213/00000539-197507000-00011