Self-templating accelerates precipitation of carbamazepine dihydrate during the dissolution of a soluble carbamazepine cocrystal

Similarly organized carbamazepine (CBZ) clusters in a soluble cocrystal with glutaric acid templated the nucleation and precipitation of poorly soluble CBZ dihydrate during dissolution.

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Bibliographic Details
Published inCrystEngComm Vol. 19; no. 8; pp. 1156 - 1159
Main Authors Yamashita, Hiroyuki, Sun, Changquan Calvin
Format Journal Article
LanguageEnglish
Japanese
Published Royal Society of Chemistry (RSC) 2017
Subjects
Clusters
Dissolution
Nucleation
Precipitation (chemistry)
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Summary:Similarly organized carbamazepine (CBZ) clusters in a soluble cocrystal with glutaric acid templated the nucleation and precipitation of poorly soluble CBZ dihydrate during dissolution.
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ISSN:1466-8033
1466-8033
DOI:10.1039/c6ce02418a