Neobacillamide A, a Novel Thiazole-Containing Alkaloid from the Marine Bacterium Bacillus vallismortis C89, Associated with South China Sea Sponge Dysidea avara

A novel thiazole alkaloid, neobacillamide A (1), together with a known related one, bacillamide C (4), was isolated from the bacterium Bacillus vallismortis C89, associated with the South China Sea sponge Dysidea avara. The structure of the new compound was elucidated on the basis of its spectroscop...

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Bibliographic Details
Published inHelvetica chimica acta Vol. 92; no. 3; pp. 607 - 612
Main Authors Yu, Lu-Lu, Li, Zhen-Yu, Peng, Chong-Sheng, Li, Zhi-Yong, Guo, Yue-Wei
Format Journal Article
LanguageEnglish
Published Zürich WILEY-VCH Verlag 01.03.2009
WILEY‐VCH Verlag
Wiley
Subjects
Alkaloids
Bacillus
Bacillus vallismortis C89
Chemistry
Chemistry, Multidisciplinary
Dysidea avara
Marine
Neobacillamide A
Physical Sciences
Science & Technology
Sea sponge
Thiazole-containing alkaloids
ISEW, South China Sea
METABOLITES
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Summary:A novel thiazole alkaloid, neobacillamide A (1), together with a known related one, bacillamide C (4), was isolated from the bacterium Bacillus vallismortis C89, associated with the South China Sea sponge Dysidea avara. The structure of the new compound was elucidated on the basis of its spectroscopic data. A plausible biosynthetic pathway is proposed. Neobacillamide A represents the first example of a thiazole‐carboxamide bearing a 2‐phenylethylamine moiety.
Bibliography:istex:089F99DFA543C33A30BC3B38DE9B13B4023A34DD
ark:/67375/WNG-DPBQWJ5G-Q
ArticleID:HLCA200800349
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200800349