Polyclonal lymphoid tumor of the choroid plexus presenting as an intraventricular mass in a young gorilla

• Published in: Acta neuropathologica Vol. 92; no. 6; p. 621
• Main Authors: Thomas, C, Anderson, D, Grigg-Damberger, M, Gujrati, M, Lee, J M, Murnane, R, Dizikes, G, Radvany, R, Walsh, T, Meehan, T P
• Format: Journal Article
• Language: English
• Published: Germany 01.12.1996
• Subjects: Animals; Ape Diseases - diagnosis; Ape Diseases - pathology; Cerebral Ventricle Neoplasms - veterinary; Child; Choroid Plexus Neoplasms - pathology; Choroid Plexus Neoplasms - veterinary; Diagnosis, Differential; Gorilla gorilla; Humans; Lymphatic Diseases - pathology; Lymphatic Diseases - veterinary; Male
• ISSN: 0001-6322
• DOI: 10.1007/s004010050570

An unusual lymphoid lesion with reactive germinal centers, occurring in the choroid plexus of a young gorilla, is reported. It presented as a large mass in the lateral ventricle with hydrocephalus and neurological symptoms. A work-up did not reveal any underlying cause for this lesion. No similar lesion of the choroid plexus has been reported in either human or veterinary literature. Histological work-up, including flow cytometry, gene rearrangement studies and T and B cell markers, favored the lesion being a non-neoplastic lymphoid proliferation of unknown etiology. The prognosis is unknown, although, following complete removal, the animal is well and free of tumor at the time of this report.