From Assessment of Radionuclide Contamination in Herbal Medicine Raw Material of Voronezh Region to Issues Concerning Standardization of Natural Radionuclides

The research was aimed at studying the accumulation of natural and artificial radionuclides in medicinal plant raw materials (MPMs) and determining approaches to standardization of natural radionuclides in them using plants growing in Voronezh Region as examples. A total of 36 collection sites of so...

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Bibliographic Details
Published inPharmaceutical chemistry journal Vol. 56; no. 8; pp. 1082 - 1086
Main Authors D’yakova, N. A., Slivkin, A. I., Trineeva, O. V.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.11.2022
Springer
Subjects
Analysis
Medicinal Plants
Medicine
Medicine, Botanic
Medicine, Herbal
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Radiation, Background
Raw materials
Voronezh Region
cesium-137
effective specific activity of natural radionuclides
strontium-90
radium-226
thorium-232
potassium-40
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Summary:The research was aimed at studying the accumulation of natural and artificial radionuclides in medicinal plant raw materials (MPMs) and determining approaches to standardization of natural radionuclides in them using plants growing in Voronezh Region as examples. A total of 36 collection sites of soil and MPM located throughout Voronezh Region and diverse in terms of anthropogenic impact were selected. Pharmacopoeial species of MPM were used as research subjects. All MPMs met the requirements of GPM.1.5.3.0001.15 for specific activity of cesium-137 and strontium-90 and for the total indicator of compliance with radiation safety requirements and its determination accuracy. The obtained specific activities of natural radionuclides in most cases exceeded the numerical values for radionuclides of anthropogenic origin. Asupplement to general pharmacopoeia monograph GPM.1.5.3.0001.15 establishing the additional numerical indicator “Effective specific activity of natural radionuclides not greater than 165 Bq/kg” is proposed to monitor contamination of MPM with natural radionuclides. These recommendations are based on an analysis of greater than 360 MPM samples from territories subject to various anthropogenic impacts. However, they are preliminary in nature and require additional research on MPMs from other regions of the Russian Federation.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-022-02757-1