An electrochemical biomimetic ATP-sensor

Molecular monolayers can be modified so that they mimic cell membranes. Two types of those biomimetic membranes were used in order to immobilize EF 0F 1-H +-ATPase on a gold electrode. The work was motivated by the objective to measure the adenosin-triphosphate (ATP) concentrations by taking advanta...

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Bibliographic Details
Published inSensors and actuators. B, Chemical Vol. 104; no. 1; pp. 111 - 116
Main Authors Bücking, Wendelin, Urban, Gerald A., Nann, Thomas
Format Journal Article
LanguageEnglish
Published Elsevier B.V 03.01.2005
Subjects
Adenosinetriphosphatase
Amperometric sensor
ATP
ATP-sensor
ATPase
Biomimetic membrane
Biosensors
Cell membranes
Electroanalytical chemistry
Electrodes
Gold
Protons
Q1
Electroanalytical chemistry
ATP-sensor
Biomimetic membrane
Amperometric sensor
ATPase
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Summary:Molecular monolayers can be modified so that they mimic cell membranes. Two types of those biomimetic membranes were used in order to immobilize EF 0F 1-H +-ATPase on a gold electrode. The work was motivated by the objective to measure the adenosin-triphosphate (ATP) concentrations by taking advantage of the ATPase activity. It was shown that one of the two forms of monolayers acted as a biosensor as the ATP concentration was directly proportional to the measured reduction current of the protons transported across the membrane by the ATPase.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0925-4005
1873-3077
DOI:10.1016/j.snb.2004.04.115