Trace elements during 2 years' oral contraception with low-estrogen preparations

In 17 healthy women, taking either a combination of 0.030 mg of ethinyl estradiol and 0.150 mg of levonorgestrel (n = 9) or a combination of 0.030 mg of ethinyl estradiol and 0.150 mg of desogestrel (n = 8) for oral contraception, the profiles of iron, calcium, copper, and zinc levels were investiga...

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Bibliographic Details
Published inGynecologic and obstetric investigation Vol. 25; no. 2; p. 113
Main Authors Liukko, P, Erkkola, R, Pakarinen, P, Järnström, S, Näntö, V, Grönroos, M
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1988
Subjects
Calcium - blood
Contraceptives, Oral, Combined - pharmacology
Contraceptives, Oral, Hormonal - pharmacology
Copper - blood
Desogestrel
Ethinyl Estradiol - administration & dosage
Female
Humans
Iron - blood
Levonorgestrel
Norgestrel - administration & dosage
Norpregnenes - administration & dosage
Trace Elements - blood
Zinc - blood
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Summary:In 17 healthy women, taking either a combination of 0.030 mg of ethinyl estradiol and 0.150 mg of levonorgestrel (n = 9) or a combination of 0.030 mg of ethinyl estradiol and 0.150 mg of desogestrel (n = 8) for oral contraception, the profiles of iron, calcium, copper, and zinc levels were investigated. The blood samplings were performed prior to oral contraception and after 3, 12, and 24 months' contraception, as well as within 2 months after discontinuation of the pill. No changes occurred in iron, calcium, and zinc levels. On the other hand, the copper level was significantly increased during oral contraception, yet returned to the initial level after discontinuation of contraception. No differences occurred between the two preparations for oral contraception.
ISSN:0378-7346
DOI:10.1159/000293756