Prostate gland and epididymis phosphatase isoenzymes: comparisons of young adult and aged rats

Relative activities of acid and alkaline phosphatases in rat reproductive tissue were studied in young adult (10-12 months) and aged (30-34 months) rats. Prostatic alkaline phosphatase alone increased in aged animals. Moreover, prostate preparations contain two isoenzymes of alkaline phosphatase whe...

Full description

Saved in:
Bibliographic Details
Published inGerontology (Basel) Vol. 34; no. 3; p. 120
Main Author Hinkle, G J
Format Journal Article
LanguageEnglish
Published Switzerland 1988
Subjects
Acid Phosphatase - metabolism
Aging
Alkaline Phosphatase - metabolism
Aluminum - pharmacology
Animals
Creatine Kinase - metabolism
Epididymis - enzymology
Glucosephosphate Dehydrogenase - metabolism
Isoenzymes - metabolism
Male
Prostate - enzymology
Rats
Rats, Inbred F344
Rats, Inbred Strains
Tartrates - pharmacology
Online AccessGet more information

Cover

More Information
Summary:Relative activities of acid and alkaline phosphatases in rat reproductive tissue were studied in young adult (10-12 months) and aged (30-34 months) rats. Prostatic alkaline phosphatase alone increased in aged animals. Moreover, prostate preparations contain two isoenzymes of alkaline phosphatase whereas only one was found in epididymal tissues. Age-associated changes in the prostatic alkaline phosphatase isoenzyme ratios were observed. No significant age-related changes in acid phosphatase tartrate sensitivity were found. Techniques for the preparation of prostate and epididymis tissue extracts are reported.
ISSN:0304-324X
DOI:10.1159/000212940