Antimycotic Activity of Naftifine Hydrochloride Solution in Combination with Poly(Ethylene Glycols)

The microbiological activity of naftifine hydrochloride solution in combination with poly(ethylene glycols) (PEG-400 and PEG-1000) was determined and compared with that of the existing foreign drug Exoderil ® . The results showed that the fungistatic activity (minimum inhibitory concentration) of th...

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Published inPharmaceutical chemistry journal Vol. 54; no. 3; pp. 310 - 311
Main Authors Kosenkova, S. I., Krasnyuk, I. I., Krasnyuk Jr, I. I., Belyatskaya, A. V., Stepanova, O. I., Li, T., Fateeva, T. V., Mazyarkin, E. V., Novikov, V. V., Korochkina, T. V.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.06.2020
Springer
Subjects
Drug Synthesis Methods and Manufacturing Technology
Glycols
Medicine
Medicine, Botanic
Medicine, Herbal
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
microbiology
naftifine hydrochloride
poly(ethylene glycol)
dermatophytes
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Summary:The microbiological activity of naftifine hydrochloride solution in combination with poly(ethylene glycols) (PEG-400 and PEG-1000) was determined and compared with that of the existing foreign drug Exoderil ® . The results showed that the fungistatic activity (minimum inhibitory concentration) of the proposed solution was about double that of Exoderil solution for Candida albicans ATCC 10231.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-020-02196-w