Brine shrimp lethality bioassay of selected Centaurea L. species (Asteraceae)

• Published in: Archives of biological sciences Vol. 60; no. 4; pp. 681 - 685
• Main Authors: Janackovic, P., University of Belgrade, Belgrade (Serbia). Faculty of Biology, Institute of Botany and Jevremovac Botanical Garden, Tesevic, V., University of Belgrade, Belgrade (Serbia). Faculty of Chemistry, Marin, P.D., University of Belgrade, Belgrade (Serbia). Faculty of Biology, Institute of Botany and Jevremovac Botanical Garden, Milosavljevic, S., University of Belgrade, Belgrade (Serbia). Faculty of Chemistry, Duletic-Lausevic, S, Janackovic, S, Veljic, M., University of Belgrade, Belgrade (Serbia). Faculty of Biology, Institute of Botany and Jevremovac Botanical Garden
• Format: Journal Article
• Language: English
• Published: University of Belgrade, University of Novi Sad 2008
• Subjects: bioactivity; BIOASSAYS; brine shrimp lethality bioassay; CENTAUREA; cnicin; cytotoxicity; ENSAYO BIOLOGICO; EXTRACTOS VEGETALES; EXTRAIT D'ORIGINE VEGETALE; http://www.fao.org/aos/agrovoc#c_15731; http://www.fao.org/aos/agrovoc#c_24614; http://www.fao.org/aos/agrovoc#c_8166; PLANT EXTRACTS; TEST BIOLOGIQUE
• ISSN: 0354-4664; 1821-4339
• DOI: 10.2298/ABS0804681J

Ether extracts of 15 Centaurea L. species (Asteraceae) methanol extracts of 12 species, and cnicin isolated from C. derventana were tested for general bioactivity using the brine shrimp lethality test. Cnicin showed the most potent activity with LC50 0.2. Also, ether extract of C. splendens showed significant activity with LC50 7.3, as did methanol extract of C. arenaria with LC50 12.4.