Fibrodysplasia ossificans progressiva: Two case reports

Fibrodysplasia ossificans progressiva (FOP) is a rare and progressively debilitating disorder affecting 1 in 2 million individuals. It is characterized by the progressive ossification of soft tissues into ectopic bone and congenital malformations of the great toes. FOP leads to significant disabilit...

Full description

Saved in:
Bibliographic Details
Published inRadiology case reports Vol. 19; no. 8; pp. 2973 - 2977
Main Authors Yaynishet, Yodit Abraham, Salah, Fathia Omer, Gebregiorgis, Bemnet Taye, Mume, Abdulmejid Suleyman, Damtew, Henok Dessalegn, Amare, Tinsae Zelalem, Manaleh, Tilahun Mengistu
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Inc 01.08.2024
Elsevier
Subjects
Case Report
Fibrodysplasia ossificans progressive (FOP)
Great toe malformation
Heterotopic ossification
Fibrodysplasia ossificans progressive (FOP)
Heterotopic ossification
Great toe malformation
Online AccessGet full text

Cover

More Information
Summary:Fibrodysplasia ossificans progressiva (FOP) is a rare and progressively debilitating disorder affecting 1 in 2 million individuals. It is characterized by the progressive ossification of soft tissues into ectopic bone and congenital malformations of the great toes. FOP leads to significant disability and can result in death due to thoracic insufficiency syndrome. These case reports examine the presentation, diagnosis, and management of FOP, highlighting the diagnostic challenges inherent in managing such rare conditions because of their unique clinical features. They underscore the need for increased awareness among healthcare practitioners to ensure early diagnosis and the implementation of effective management strategies.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2024.04.019